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DTSTART;TZID=America/Los_Angeles:20260319T113000
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DTSTAMP:20260420T050841
CREATED:20260228T173313Z
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UID:77818-1773919800-1773925800@svec.org
SUMMARY:X-ray Microscopy of Magnetic Nanostructures
DESCRIPTION:Silicon Metasurfaces for DNA Synthesis\nAbstract:\nReady access to long\, accurate\, and diverse synthetic DNA is essential for the rapid growth of synthetic biology — a field that genetically programs living cells with new functions. Modern microarray-based DNA synthesizers can generate diverse pools of oligonucleotide (single stranded DNA) sequences in parallel. However\, each sequence is produced in limited quantity\, and their yields decline with increasing oligo length due to cumulative synthesis errors. These limitations complicate downstream sequence segregation and gene assembly. Attempts to address these challenges by enlarging and spacing synthesis sites farther apart reduce the total number of sequences that can be generated simultaneously\, thereby compromising synthesis diversity.\n[]\nIn this talk\, I will introduce B-MOS (Metasurface Oligonucleotide Synthesizer for Engineered Biology) — a novel platform that integrates silicon nanophotonics with solid-phase DNA synthesis to overcome these challenges.\nB-MOS employs dielectric metasurfaces composed of arrays of high-index and low loss silicon nanoantennas (metasurfaces) patterned on glass as optically programmable synthesis sites. The unique optical signature of each metasurface — its spectral and polarization response — is lithographically encoded into the geometry and orientation of the silicon nanoantennas. Under global illumination\, only the metasurface tuned to the wavelength and polarization of the laser absorbs the optical energy and transduces it into highly localized heat to site-selectively activate the synthesis reactions. Tuning the laser enables switching between the synthesis sites without moving parts or complex optical projection systems that lead to alignment errors.\nAs these nanostructures support sharp (high-Q) optical resonances\, crosstalk between the synthesis sites is minimized. These sharp resonances allow the dense spectral packing of independently addressable synthesis within the tunable range of the laser\, thereby maximizing synthesis diversity.\nUsing temperature as a programmable biochemical control knob\, I will demonstrate site-selective enzymatic incorporation of fluorescent nucleotides onto surface-bound DNA using the enzyme terminal deoxynucleotidyl transferase. I will further discuss how integrating B-MOS with microfluidics can enable post-synthesis site-selective amplification and spatial segregation of oligo strands for reliable gene assembly.\nFinally\, I will outline how B-MOS can be extended to RNA and peptide synthesis as well as other enzyme-driven processes. By resonant nanophotonics with programmable biochemical control\, B-MOS establishes a scalable physical foundation for high-precision biomolecular manufacturing and next-generation molecular technologies.\nSpeaker:\nDr. Punnag Padhy\nPostdoctoral Scholar\nDepartment of Materials Science and Engineering\nStanford University\nAGENDA:\nThursday March 19\, 2026\n11:30 AM: Networking\, Pizza & Drinks\nNoon — 1 pm: Seminar\nPlease register on Eventbrite before 9:30 AM on Thursday March 19\, 2026\n$4 IEEE members $6 non IEEE members\n(discounts for unemployed and students )\nBldg: ==> Use corner entrance: Kifer Road / San Lucar Court ==> Do not enter at main entrance on Kifer Road\, EAG Labs\, 810 Kifer Road\, Sunnyvale\, California\, California\, United States\, 95051
URL:https://svec.org/event/x-ray-microscopy-of-magnetic-nanostructures-2/
LOCATION:Bldg: ==> Use corner entrance: Kifer Road / San Lucar Court ==> Do not enter at main entrance on Kifer Road\, EAG Labs\, 810 Kifer Road\, Sunnyvale\, California\, California\, United States\, 95051
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DTSTART;TZID=America/Los_Angeles:20260319T173000
DTEND;TZID=America/Los_Angeles:20260319T203000
DTSTAMP:20260420T050841
CREATED:20260217T171807Z
LAST-MODIFIED:20260217T171807Z
UID:77774-1773941400-1773952200@svec.org
SUMMARY:Characterizing 2nd Law Efficiency of AI Datacenters
DESCRIPTION:Datacenter workload fluctuations challenge the design and operation of our critical grid infrastructure. Significant gaps exist in assessment of these fluctuations as to their lifetime and short-term impact on the infrastructure and environment. Some mitigation approaches focus on throttling the datacenter workload\, thus impacting the performance. Other approaches include use of alternate generation sources or energy storage systems. While disparate\, these approaches are reactive and lack foresight and the intelligence to plan and strategize for optimal power management. We introduce an approach to quantify the transitional entropy generated during datacenter power fluctuations as a metric to evaluate datacenter performance using power demand measurements. A comparative assessment is provided between a BESS optimized datacenter and a regular datacenter to demonstrate the reduction of irreversibilities due to power fluctuations. Workloads are used to characterize the datacenter power demand at the point of interaction with utility. This approach can be scaled from datacenters to servers to chips.\nSpeaker(s): Ratnesh K Sharma\,\nAgenda:\nNo-host social at 5:30pm\nPresentation at 6:00pm\nDinner at 7:00pm\nPresentation continues at 7:45pm\nAdjourn by 8:30pm\nZio Fraedo's\, 611 Gregory Lane\, Pleasant Hill\, California\, United States\, 94523
URL:https://svec.org/event/characterizing-2nd-law-efficiency-of-ai-datacenters/
LOCATION:Zio Fraedo's\, 611 Gregory Lane\, Pleasant Hill\, California\, United States\, 94523
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20260319T173000
DTEND;TZID=America/Los_Angeles:20260319T203000
DTSTAMP:20260420T050841
CREATED:20260227T173306Z
LAST-MODIFIED:20260227T173306Z
UID:77813-1773941400-1773952200@svec.org
SUMMARY:Understanding Tier 4 Emissions for Generator Sets
DESCRIPTION:Stationary generator sets operated in regions governed by a local environmental review board may be subject to strict emissions regulations. Many of these areas\, known as non-attainment zones\, have enacted clean air requirements that adhere to the EPA’s Tier 4 standard\, effective in 2015. For these stringent applications\, Cummins provides Tier 4 gensets that reduce the exhaust constituents to the industry’s lowest emissions standard. This presentation will offer insights on how to design a reliable system that meets local and national code requirements.\nSpeaker(s): Shen Yoon\,\nAgenda:\nNo-host social at 5:30pm\nPresentation at 6:00pm\nDinner at 7:00pm\nPresentation continues at 7:45pm\nAdjourn by 8:30pm\nZio Fraedo's \, 611 Gregory Lane\, Pleasant Hill\, California\, United States\, 94523
URL:https://svec.org/event/understanding-tier-4-emissions-for-generator-sets/
LOCATION:Zio Fraedo's \, 611 Gregory Lane\, Pleasant Hill\, California\, United States\, 94523
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